The controvertible role of kava (Piper methysticum G. Foster) an anxiolytic herb, on toxic hepatitis
نویسندگان
چکیده
منابع مشابه
Piper methysticum (kava kava) Monograph
Description and Constituents Piper methysticum (kava kava) is a perennial plant native to the Pacific Island region, and has been used ceremonially for thousands of years. Traditionally, a beverage is prepared, then drunk before the evening meal. Indigenous methods of mastication of the kava root have given way to grinding or pounding the plant substance, which is then mixed with water or cocon...
متن کاملKava (Piper methysticum).
BACKGROUND: Kava is a plant indigenous to the Pacific Rim and the Hawaiian Islands whose root and rhizome are used to prepare a non-fermented beverage with relaxant effects that is used for social and recreational purposes. Kava roots are chewed or ground into a pulp and added to cold water, and the resulting brew—reported to mimic the effects of an alcoholic beverage—has been used as a ceremon...
متن کاملExtracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro.
Root extracts from kava-kava (Piper methysticum G. Forst) are clinically used for the treatment of anxiety and restlessness. Due to reported cases of liver toxicity, kava-kava extracts were withdrawn from the market in several countries in 2002. Because the efflux transporter P-glycoprotein (P-gp) is involved in the absorption, distribution, and excretion of many drugs and often participates in...
متن کاملMeasuring the Chemical and Cytotoxic Variability of Commercially Available Kava (Piper methysticum G. Forster)
Formerly used world-wide as a popular botanical medicine to reduce anxiety, reports of hepatotoxicity linked to consuming kava extracts in the late 1990s have resulted in global restrictions on kava use and have hindered kava-related research. Despite its presence on the United States Food and Drug Administration consumer advisory list for the past decade, export data from kava producing countr...
متن کاملAnticancer activities of constituents of kava (Piper methysticum)
Crude extracts of kava (Piper methysticum G. Forster, Piperaceae) showed good activity against ovarian tumour and leukaemia cancer cell lines. Bioassay-guided isolation resulted in the isolation of six known kava lactones and two flavokavains. The structure of the compounds were elucidated by spectroscopic techniques and by comparison with data in the literature.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2007
ISSN: 0102-695X
DOI: 10.1590/s0102-695x2007000300020